Course: Úvod do bioinženýrství

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Course title Úvod do bioinženýrství
Course code KCH/UBIO
Organizational form of instruction Lecture + Lesson
Level of course Bachelor
Year of study not specified
Semester Winter
Number of ECTS credits 5
Language of instruction Czech
Status of course Compulsory, Optional
Form of instruction Face-to-face
Work placements Course does not contain work placement
Recommended optional programme components None
Course availability The course is available to visiting students
Lecturer(s)
  • Kuželová Košťáková Eva, doc. Ing. Ph.D.
Course content
1. Introduction - What is Bioengineering? Biomedical Engineering - Engineering in modern medicine, explanation of the breadth of bioengineering, clarification of concepts and basic division. 2. Bioengineering as "imitation" of nature - biomimetic principles. 3. Bioengineering - materials for biomedical applications, definition of biomaterials, biocompatibility, biodegradability etc., brief history of biomaterials. 4. Structure of solids - structure of materials in general, bonds, crystalline structure, structural hierarchy - microstructure. 5. Biomolecular principles - importance of water, importance of pH, importance of lipids, importance of macromolecules, biochemical energetics. 6. Characterization of materials I - mechanical properties, thermal properties, phase diagrams, surface characteristics and adhesion). 7. Characterization of materials II - electrical properties, optical properties, density, porosity, diffusion. 8. Metal biomaterials - stainless steel, titanium, alloys, corrosion problems. 9. Ceramic biomaterials - structure and properties, aluminum oxides, zirconium oxides, calcium phosphate, glass ceramics, carbon materials. 10. Polymeric biomaterials - basics of polymerization and properties of polymers, effect of structural modifications and temperature, natural and synthetic polymers for biomaterials. 11. Composites as biomaterials - structure, mechanical properties, applications, biocompatibility. 12. Surface treatment of materials for medical applications. 13. Tissue response to implants (biomaterials) - normal healing, response of the organism to the implant, blood compatibility, carcinogenicity. 14. Bioengineering in medical applications - introduction to drug delivery systems, tissue engineering, nanobiotechnology and wound covers; principles, history, examples of used materials and their testing, challenges in imitation of nature, examples of used materials and their testing.

Learning activities and teaching methods
Self-study (text study, reading, problematic tasks, practical tasks, experiments, research, written assignments), Laboratory work
  • Class attendance - 56 hours per semester
  • Preparation for laboratory testing; outcome analysis - 48 hours per semester
  • Preparation for credit - 10 hours per semester
Learning outcomes
The aim of the course is to acquaint students with the field of bioengineering. Especially with the use of engineering in modern medicine, with regard to the creation of biomaterials for medical applications.
Theoretical knowledge and practical skills in the field.
Prerequisites
unspecified

Assessment methods and criteria
Combined examination

elaborated and defended protocols for every exercise Each laboratory is initiated by a short written test. Test will verify the knowledge of principles of current laboratory task. In the event of not sufficient knowledge necessary to perform laboratory exercises, student may be excluded from the laboratory.
Recommended literature
  • BU P. J. LAKES R. S. Biomaterials: an introduction. 3rd ed.. New York: Springer, 2007. ISBN 978-0387378794.
  • LANZA R. ROBERT P. LANGER S. VACANTI J. ed. Principles of tissue engineering. 4th ed.. Amsterdam: Academic Press, 2014. ISBN 978-0123983589.
  • RATNER B. D. ed. Biomaterials science: an introduction to materials in medicine. 3rd ed.. Amsterdam; Boston: Elsevier/Academic Press, 2013. ISBN 978-0123746269.


Study plans that include the course
Faculty Study plan (Version) Category of Branch/Specialization Recommended year of study Recommended semester