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Lecturer(s)
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Lukáš David, prof. RNDr. CSc.
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Course content
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Lectures: Topic 1 - Physical view of life and living organisms (self-study according to [1]) 1. Molecular basis of living organisms and model organisms. 2. Models of biological systems. 3. Structure of cells and organisms. 4. Time scales of biological processes. Topic 2 - Equilibrium states in living organisms 5. Mechanical and chemical equilibria in living organisms. 6. Laws of entropy. 7. Two-state biological systems - ion channels and binding between receptors and ligands. 8. Structure of macromolecules, random walks and diffusion. Topic 3 - Dynamic biological phenomena 9. Dynamic properties of aquatic environment in living organisms. 10. Statistics of biological dynamic phenomena. 11. Life processes in dense disordered systems. 12. Dynamics of molecular engines. Topic 4 - Organization in living organisms 13. Organization of biological networks. 14. Spatial and temporal arrangement of biological systems. Written work and exercises: The lectures will be practiced at seminars.
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Learning activities and teaching methods
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Monological explanation (lecture, presentation,briefing), Self-study (text study, reading, problematic tasks, practical tasks, experiments, research, written assignments), Seminár, Students' self-study
- Class attendance
- 56 hours per semester
- Preparation for formative assessments
- 10 hours per semester
- Preparation for exam
- 80 hours per semester
- Semestral paper
- 40 hours per semester
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Learning outcomes
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Learning outcomes of the course unit The aim of the course is to acquaint and acquire basic physical patterns of biological phenomena.
To explain and deduce basic knowledge on field, including simpler problem solving.
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Prerequisites
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knowledge of high school physics and biology
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Assessment methods and criteria
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Combined examination, Written assignment, Test
During the study students will write a written work on a given topic and will prepare two control tests for which credit will be given. The exam consists of a written and an oral part.
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Recommended literature
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BIALEK W. Biophysics: Searching for Principles.. 1st edition. Princeton: Princeton University Press., 2012. ISBN 9780691138916.
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PHILLIPS R. KONDEV J. THERIOT J. GARCIA H. Physical Biology of the Cell. 2nd edition, New York: Garland Science, 2013. ISBN 9780815344506.
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RUBIN A. B. Compendium of Biophysics. 1st edition, Hoboken: Wiley-Scrivener, 2017. ISBN 9781119160250.
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