Course: Water-Biomaterials Interaction

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Course title Water-Biomaterials Interaction
Course code KCH/IBV
Organizational form of instruction Lecture + Lesson
Level of course Master
Year of study not specified
Semester Summer
Number of ECTS credits 5
Language of instruction Czech, English
Status of course Compulsory
Form of instruction Face-to-face
Work placements Course does not contain work placement
Recommended optional programme components None
Lecturer(s)
  • Kuželová Košťáková Eva, doc. Ing. Ph.D.
Course content
Lectures: 1. Capillarity - deformation of the interface (surface tension and surface energy). 2. Laplace capillary pressure, Adhesion and adhesion energy. 3. Wetting - contact between three phases, spreading coefficient, measurement of contact angles (introduction). 4. Measurement of contact angles - conditions, problems of rough and porous surfaces, dynamic contact angles, hysteresis of contact angles. 5. Perfect wetting - conditions. 6. Capillary length, droplet sizes and modes of wetting of solid surfaces, meniscus and its characterization. 7. Rayleigh-Plateau instability. 8. Lucas-Washburn equation - dynamics of wetting of porous materials at different angles of rotation towards the penetrating liquid. 9. Washburn's method of estimating the contact angle for porous materials and for porous swelling materials (fibrous materials, powders, foams, etc.). 10. Wetting of textured surfaces - equilibrium contact angle on the surface of porous material. 11. Transport phenomena - chemical gradient, temperature gradient, reactive wetting, transport by electric field. 12. Biomaterials in the field of wetting, methods of characterization of biomaterial surfaces. 13. Wetting of biomaterials - influence of surface characteristics, water in biomaterials. 14. Simulation of wetting of porous materials (Ising's model). Exercises: The material explained in lectures will be practiced in the exercises.

Learning activities and teaching methods
Lecture, Practicum
  • Contacts hours - 56 hours per semester
  • Preparation for exam - 48 hours per semester
Learning outcomes
The course deals with the basics of capillary, surface and interfacial phenomena. The aim is to better understand the relationships between the surfaces of biomaterials and their manifestations or characteristics, especially in contact with cell cultures, both in in-vitro or in-vivo tests and in the final application. Students are acquainted from the ground up with the concepts of surface and interfacial tensions and energies, their measurement and influencing. Students are introduced to the conditions for partial and perfect wetting as well as for perfect hydrophobicity. Hydrodynamic instabilities in wetting biomaterials with various liquids are also described.

Prerequisites
unspecified

Assessment methods and criteria
Combined examination

Attendance at seminars, written and oral exam.
Recommended literature
  • De GENNES P.-G. BROCHARD-WYART F. QUERE D. Capillarity and Wetting Phenomena. Springer, 2004. ISBN 0-387-00592-7.
  • PAN N. GIBSON P. Thermal and moisture transport in fibrous materials. Woodhead Publishing Limited, Cambridge. ISBN 978-1-84569-057-1.
  • RARTNER B. D., HOFFMAN A. S. SCHOEN F. J. LEMONS J. E. Biomaterials Science: An Introduction to Materials in medicine. Elsevier Academic Press, 2004. ISBN 012-582463-7.


Study plans that include the course
Faculty Study plan (Version) Category of Branch/Specialization Recommended year of study Recommended semester