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Lecturer(s)
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Hauzerová Šárka, Ing.
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Řezanka Michal, doc. RNDr. Ph.D.
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Jenčová Věra, doc. Ing. Ph.D.
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Course content
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1. Nomenclature of organic compounds. 2. R/S and E/Z isomerism, conformation. 3. Alkenes and alkynes - examples, properties, preparation and reactivity. 4. Halogenated derivatives and amines - examples, properties, preparation and reactivity. 5. Aromatics and alcohols - examples, properties and reactivity. 6. Aldehydes and ketones - examples, properties and reactivity. 7. Carboxylic acids - examples, properties and reactivity. 8. Carbohydrates. Structure and chemical properties, nomenclature, D- and L-, Fischer formulas, cyclic structures of carbohydrates, - and -glycosidic linkage, oligo- and polysaccharides. 9. Lipids, distribution of lipids, phospholipids, steroids. 10. Proteins - -amino acids, hierarchical structure of proteins, ligand interactions, biological function of proteins. 11. Enzymes - basics of enzyme kinetics, Biological membrane - structure, membrane proteins, transport. 12. Nucleic acids - structure, central dogma, replication, transcription, translation. 13. Biochemical energetics - ATP, citrate (Krebs) cycle, respiratory chain. 14. Summary of learning.
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Learning activities and teaching methods
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Self-study (text study, reading, problematic tasks, practical tasks, experiments, research, written assignments), Laboratory work, Lecture, Practicum
- Class attendance
- 56 hours per semester
- Preparation for credit
- 28 hours per semester
- Preparation for exam
- 80 hours per semester
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Learning outcomes
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The aim of the course is to acquire knowledge in organic chemistry and biochemistry, and the biochemical element will also be emphasized in the teaching of organic chemistry. The biochemistry part focuses on the understanding of the structure and function of biomacromolecules and also deals with the principles of basic processes occurring in cells. The knowledge gained in lectures will be deepened during the exercises and laboratories.
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Prerequisites
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unspecified
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Assessment methods and criteria
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Written exam, Test
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Recommended literature
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KODÍČEK, M., VALENTOVÁ, O., HYNEK, R. Biochemie: chemický pohled na biologický svět. Praha, 2018. ISBN 8075920139.
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McMURRY, J. Organická chemie. VŠCHT, Praha, 2007.
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Voet, D.; Voet J. G. Biochemistry. Hoboken: Wiley. 4th ed., 2011. ISBN 978-0-470-57095-1.
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