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Lecturer(s)
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Erben Jakub, Ing. Ph.D.
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Klíčová Markéta, Ing.
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Horáková Jana, doc. RNDr. Ph.D.
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Course content
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Lectures: 1. Introduction to tissue engineering 2. Requirements for biomaterials, sterilization 3. Natural materials used for tissue engineering scaffolds 4. Synthetic materials used for tissue engineering scaffolds 5. Scaffold fabrication technologies 6. Biomaterials characterization I 7. Biomaterials characterization II 8. Surface modification of scaffolds 9. Drug delivery systems 10. Composite materials in tissue engineering Practical courses: 1. Fabrication of nanofibrous scaffolds by electrospinning (planar materials) 2. Fabrication of nanofibrous scaffolds by electrospinning (tubular materials) 3. Fabrication of nanofibrous scaffolds by centrifugal spinning 4. Fabrication of polymeric foils by solvent casting + particle leaching 5. Drug delivery systems, measurement of amount of aktive substance 6. Assessment of biomaterials morphology 7. Assessment of surface properties of biomaterials 8. Measurement of biomaterials adhesion
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Learning activities and teaching methods
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Monological explanation (lecture, presentation,briefing), Self-study (text study, reading, problematic tasks, practical tasks, experiments, research, written assignments), Demonstration, Laboratory work, E-learning
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Learning outcomes
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Bachelor course "Fibrous materials for tissue engineering" is focused on multidisciplinary field of scaffolds used for regenerative medicine. Synthetic and natural materials, fabrication technologies and biomaterials charcterization will be introduced.
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Prerequisites
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Any one
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Assessment methods and criteria
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Combined examination, Oral exam, Didactic test
Laboratory practice, exam
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Recommended literature
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Gary E. Encyclopedia of Biomaterials and Biomedical Engineering, Marcel Dekker, New York, 2004.
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Lanza R.P., Langer R., Vacanti J. Principles of tissue engineering, Second edition, Academic Press, 1997.
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Peter X. Ma. Scaffolds in Tissue Engineering, Taylor and Francis, New York, 2006.
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RATNER, Buddy. Biomaterials Science. 3rd Edition.. Academic Press,, 2013. ISBN 978-0-12-374626-9.
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