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Lecturer(s)
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Beneš Jiří, prof. MUDr. RNDr. CSc.
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Jirák Daniel, doc. Ing. Ph.D.
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Course content
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Lectures: 1) Physics in medicine, structure of matter, quantum numbers, structure of electron shell of atom, excitation, ionization 2) Nuclear nucleus, nuclear forces, nuclear bonding energy, magnetic properties of nuclei; nuclear magnetic resonance imaging 3) Basic use of X-rays in medicine (X-ray device, interaction of X-rays with matter, use in diagnostics and therapy) 4) Bioacoustics (physical and physiological acoustics); ultrasound, hearing principle; principles of ultrasonic imaging; clinical use of shock waves and ultrasound 5) Molecular biophysics (latent states, dispersion systems), transport phenomena, colligative properties of solutions, osmotic pressure, blood circulation 6) Application of molecular biophysics (physical laws in blood circulation and respiration, sedimentation of blood rheology, hyperbaric chamber 7) Electrical manifestations of organism, calculation of action potentials, physical basics of electrodiagnostic methods; resting membrane potential, action potential and its propagation 8) Optics, properties of light, interaction with environment, optical imaging, optics of human eye 9) Optical devices in diagnostics and therapy, UV, IR light, principle and properties of laser 10) Bioenergetics: thermodynamic quantities and functions 11) Heat loss of organism, therapeutic use of heat, temperature measurement and regulation 12) Radiotherapy in the clinic; law of radioactive decay, radioactive balance 13) Types of decay, radiation interaction, radiation detection, use of radionuclides in medicine, Gamakamera, PET 14) Physical application in clinical practice and intensive care unit, heat, sound and radiation damage
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Learning activities and teaching methods
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Monological explanation (lecture, presentation,briefing), Dialogue metods(conversation,discussion,brainstorming)
- Home preparation for classes
- 18 hours per semester
- Semestral paper
- 10 hours per semester
- Class attendance
- 28 hours per semester
- Preparation for credit
- 4 hours per semester
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Learning outcomes
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The aim of the course is to build on the basics of medical physics, understanding the interactions of physical fields and matter with tissue, the reaction of organism and tissues on the effects of physical force fields. The course will deal with biological processes in the organism, osmotic pressure, transport phenomena, physics of blood flow in blood vessels. Molecular properties of liquids gases for clinical applications, cell biophysics, membrane phenomena (transport, potential), propagation of action potential, application of thermodynamics for clinical practice.
Students obtain knowledge in given course in accordance with requirements and course programme.
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Prerequisites
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Preconditions are frased in the annotation of the course and in the curriculum of the studying programme.
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Assessment methods and criteria
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Written exam
Classified credit: - written test, - oral examination.
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Recommended literature
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BENEŠ, Jiří, Daniel JIRÁK a František VÍTEK. Základy lékařské fyziky. Praha: Karolinum, 2015. ISBN 978-80-246-2645-1.
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BENEŠ, Jiří, Jaroslava KYMPLOVÁ a František VÍTEK. Základy fyziky pro lékařské a zdravotnické obory: pro studium i praxi. Praha: Grada, 2015. ISBN 978-80-247-4712-5.
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BENEŠ, Jiří. Základy lékařské biofyziky. Praha: Karolinum, 2011. ISBN 978-80-246-2034-3.
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HRVOLOVÁ, Barbora. Biofyzika. Ostrava: Technická univerzita Ostrava, 2013. ISBN 978-80-248-3105-3.
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KORANDA, Pavel. Nukleární medicína. Olomouc: Univerzita Palackého v Olomouci, 2014. ISBN 978-80-244-4031-6.
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KUPKA, Karel, Jozef KUBINYI a Martin ŠÁMAL. Nukleární medicína. Praha: P3K, 2015. ISBN 978-80-873-4354-8.
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ROSINA, Jozef. Biofyzika: pro zdravotnické a biomedicínské obory. Praha: Grada, 2013. ISBN 978-80-247-4237-3.
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SEIDL, Zdeněk. Radiologie pro studium i praxi. Praha: Grada, 2012. ISBN 978-80-247-4108-6.
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VLČEK, Petr. Praktická cvičení z nukleární medicíny. Praha: Karolinum, 2010. ISBN 978-80-246-1819-7.
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