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Lecturer(s)
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Novosád Aleš, PharmDr.
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Ondrejček Pavel, PharmDr. Ph.D.
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Course content
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Lectures: Pharmacology 1) Characteristics of the field, definitions of drugs, medicines, names of medicines, pharmaceutical forms, MS. lékopis; drug prescription and prescription; general pharmacology - pharmacokinetics; importance for drug administration, drug delivery methods, pharmacodynamics; mechanism of drug effects, types of therapy; drug dosing; drug interaction, drug dependence 2) Drugs affecting the CNS - review; general anesthetics, hypnotics, antiepileptics; review of psychopharmaceuticals and drugs for degenerative diseases; drugs used in pain therapy; pharmacological procedures for affecting pain; drugs affecting the peripheral nervous system; local anesthetics, myorelaxants 3) Drugs affecting the heart and blood vessels; antihypertensive drugs, cardiac insufficiency drugs and other groups; diuretics; blood substitutes, electrolyte infusion solutions 4) Overview of drugs affecting the respiratory system; antiasthmatics, antitussives, expectorants; review of drugs affecting the gastrointestinal tract; spasmolytics, antacids, antiulcerosis, etc. 5) Drugs affecting the endocrine system; insulin; oral antidiabetics; steroid hormones; antibiotics and anti-infectious chemotherapeutics; antiseptics and disinfectants; an overview of anticancer drugs; erectile dysfunction, medicines used in ophthalmology and medicines in special groups of patients - ie during pregnancy, breastfeeding, in children and in old age Toxicology 6) General toxicology - basic concepts, mechanism of action of poisons; diagnostics including the basics of chemical examination methods in toxicology and first aid in intoxication, antidotes 7) Special toxicology: inorganic poisons, organic poisons (industrial); substances of biological origin (plant and animal poisons), pharmacological preparations; substance abuse and drug addiction
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Learning activities and teaching methods
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Dialogue metods(conversation,discussion,brainstorming)
- Class attendance
- 28 hours per semester
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Learning outcomes
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General and clinical pharmacology acquaints with basic knowledge of general and clinical pharmacology, which is followed by other subjects. It contains general pharmacology, an overview of drug groups used in medicine, including their indications, contraindications, dosages and side effects, and the use of pharmacology in practice, as well as links with other scientific subjects such as morphology and pathology.
Students obtain knowledge in given course in accordance with requirements and course programme.
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Prerequisites
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General and Clinical Pharmacology introduces basic knowledge of general and clinical pharmacology, followed by other subject areas. The content is general pharmacology, an overview of drug groups used in medicine including their indications, contraindications, dosages and side effects, and the use of pharmacology in practice, as well as linking with other subjects such as morphology and pathology.
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Assessment methods and criteria
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Oral exam
To get the credit, 80% attendance at the lectures is required. The exam is conducted through an oral exam where the student takes two questions. 1st question is from the field of general pharmacology, 2nd question is from the field of specialized pharmacology. It requires a basic understanding of the subject, the basic distribution of the groups of medicinal products, the basic mechanisms of action, the most common side effects, contraindications and interactions. Self-study. According to the Study Regulations, I will recall Article 17. (17) If a student withdraws from the examination after he / she starts, if he / she fails to attend the examination without proper excuse or if he / she seriously violates the test rules, he / she is classified as "failing". For serious reasons, especially medical ones, the student can apologize additionally, but no later than the fifth day after the scheduled date for the examination. The examiner shall decide the reasons for the excuse.
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Recommended literature
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GUCKÝ, Tomáš. Toxikologie omamných a psychotropních látek. Olomouc: Unicerzita Palackého v Olomouci, 2015. ISBN 978-80-244-4537-3.
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LINHART, Igor. Toxikologie: Interakce škodlivých látek s živými organismy, jejich mechanismy, projevy a důsledky. Praha: VŠCHT, 2014. ISBN 978-80-7080-877-1.
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PERLÍK, František. Základy farmakologie. Praha: Galén, 2011. ISBN 978-80-7262-759-2.
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SEZIMOVÁ, Hana, K. MALACHOVÁ a Zuzana RYBKOVÁ. Toxikologie a genotoxikologie. Ostrava: Ostravská univerzita, 2015. ISBN 978-80-7464-740-6.
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SLÍVA, Jiří a Martin VOTAVA. Farmakologie: Lékařské repetitorium. Praha: Triton, 2011. ISBN 978-80-7387-500-8.
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SLÍVA, Jiří a Martin VOTAVA. Farmakologie. Praha: Triton, 2010. ISBN 978-80-7387-424-7.
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