Course: Biocybernetics

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Course title Biocybernetics
Course code MTI/BIK
Organizational form of instruction Lecture + Lesson
Level of course Master
Year of study not specified
Semester Summer
Number of ECTS credits 2
Language of instruction Czech
Status of course Compulsory
Form of instruction Face-to-face
Work placements Course does not contain work placement
Recommended optional programme components None
Lecturer(s)
  • Mrázek Petr, Ing. Ph.D.
Course content
Lectures and seminars: 1 Introduction to biocybernetics Cells and cell regulation properties of living matter, the basic substance of living matter, functional organization cells, genetic information in the cell, cellular regulation and mathematical models, regulation at the level of enzymes, regulation of synthesis enzymes models repression of enzyme synthesis 2 Modeling biological systems Mathematical, deterministic and stochastic models of biological systems, modeling and simulation methodology biological systems, the process of creating a model 3 Nonlinear Dynamical Systems The mathematical description , analysis in phase space, analytical and numerical methods, phase trajectory, stability, chaotic behavior, catastrophic behavior. 4 Chemical Kinetics Basic concepts, mathematical models of simple reactions, autocatalytic reactions, enzyme kinetics, and oscillatory wave phenomena in chemical systems. 5 Measurement of non-electrical quantities on living tissue RT, CT, NMR, PET, ultrasound, thermography. Methods of treatment outcomes, measurement and digital signal processing , membrane potentials, EEG , EKG, EMG, diagnosis of abnormalities. 6 Population dynamics Models of single communities, continuous models of the same population impact on the population density and management population density, discrete models of the same population, discrete models of population age structure, growth and cultivation microorganisms, microbial growth models, continuous model of predator -prey 7 Pharmacokinetics Compartmental modeling, Multicompartmental analysis, models of drug penetration biological membranes, linear pharmacokinetic models , kinetics of distribution of drugs after an intravenous injection and infusion, nonlinear pharmacokinetic models 8 Neurokybernetika Transmission of signals in neurons, mathematical models of neurons, neuron deterministic models, stochastic models neuron 9 Model of respiratory regulation Physiological introduction, description of the model , the pulmonary compartment, brain compartment, the compartment other tissues, a description of segments of blood circulation, blood flow, a physiological regulator, overall diagram of the model 10 Pulse model bloodstream Physiological introduction, description of the model, the basic concepts, basic equations for the model description pulsation of heart, description flap, a description of the flow through the arteries, veins description, overall schema model 11 Model dependence of heart rate on physical activity Physiological introduction, description of model evaluation results 12 Model glycemic control and regulation of gastric acidity Physiological introduction, description of model evaluation results 13 Model renal function in stabilizing blood pressure Physiological introduction, description of model evaluation results. 14 Model isometric contraction of skeletal muscle. Physiological introduction, description of model evaluation results

Learning activities and teaching methods
Dialogue metods(conversation,discussion,brainstorming), Working activities (workshops)
  • Class attendance - 48 hours per semester
  • Preparation for exam - 6 hours per semester
  • Home preparation for classes - 6 hours per semester
Learning outcomes
The aim of the course is to familiarize students with basic physiological processes in the human organism and their modeling in biocybernetics. Students will gain knowledge that will allow them to incorporate different levels of information on biological object to model and understand the function of the object. In addition, should also have even more general perspective on feedback control as the principle with which normally encountered even in living organisms and results of the theory of systems and control and use for understanding many processes that take place in living organisms. Students are able to define the scope biocybernetics. Students are able to define and sleep for individual processes occurring within biocybernetics.
Students obtain knowledge in given course in accordance with requirements and course programme.
Prerequisites
Preconditions are frased in the annotation of the course and in the curriculum of the studying programme.

Assessment methods and criteria
Combined examination, Practical demonstration of acquired skills

Active participation in laboratory practices, the development of the tasks assigned to exercise or nestihnutí form of a paper, Credit, Final Exam.
Recommended literature
  • BRONZINO, J. D. The biomedical engineering handbook: Biomedical engineering fundamentals. Boca Raton: Taylor & Francis, 2006. ISBN 0-8493-2122-0.
  • Eck, V., Razím, M. Biokybernetika. Praha: ČVUT, 1996. ISBN 80-01-01445-2.
  • Holčík, J., Fojt, O. Modelování biologických systémů (Vybrané kapitoly). Brno: ČVUT, 2001. ISBN 80-214-2023-5.
  • Pazourek J. Simulace biologických systémů. Praha, Grada, 1992.
  • Svatoš, J. Biologické signály. Geneze, analýza a zpracování, skripta. ČVUT, Praha, 1998.


Study plans that include the course
Faculty Study plan (Version) Category of Branch/Specialization Recommended year of study Recommended semester
Faculty: Faculty of Health Studies Study plan (Version): Biomedical Engineering (14) Category: Special and interdisciplinary fields 2 Recommended year of study:2, Recommended semester: Summer