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Lecturer(s)
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Hlaváčková Veronika, Mgr. Ph.D.
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Course content
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1. Genetics (basic concepts, Mendel's laws). 2. Gene interactions (intraallelic, interallelic, duplication interactions, inheritance of quantitative traits). 3. Gene linkage (Morgan's laws, crossing-over, linkage phases, strength of linkage). 4. Genetic aspects of division (cell cycle, mitosis and meiosis, sex-linked inheritance). 5. Cytological basis of heredity (chromosome, karyotype, chromosomal sex determination). 6. Molecular basis of heredity (nucleic acids, their structure). 7. From information to phenotype (replication, transcription, translation, genetic code). 8. Gene expression and its regulation. 9. Extranuclear inheritance. 10. Basics of population genetics (allogamous and autogamous populations, Hardy-Weinberg law, genetic drift). 11. Mutations and mutagenesis (types and nature of mutations, mutagens, repair of damaged DNA). 12. Methods of molecular genetics (DNA isolation, PCR, qPCR, sequencing, cloning).
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Learning activities and teaching methods
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Self-study (text study, reading, problematic tasks, practical tasks, experiments, research, written assignments), Lecture, Practicum
- Class attendance
- 42 hours per semester
- Preparation for credit
- 30 hours per semester
- Preparation for exam
- 40 hours per semester
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Learning outcomes
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The course is designed to introduce students to the basic areas of genetics, the laws of transmission of hereditary traits at the level of the organism, at the level of the cell and the principles of molecular genetic phenomena. Basic genetic knowledge is necessary for understanding the laws of inheritance and variation and the course is therefore a suitable complement to the knowledge of teachers at all levels of school. Topics are supplemented with simple experiments suitable for primary and secondary school students and an introduction to basic molecular genetic methods.
Theoretical knowledge and practical skills in the field.
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Prerequisites
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basic knowledge of biology and chemistry
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Assessment methods and criteria
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Oral exam, Written assignment, Test
2x written test during the semester, the result will be included in the overall result of the exam, oral exam; credit will be awarded for active participation in exercises, preparation of laboratory protocols from individual tasks and credit test.
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Recommended literature
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Kočárek E. Genetika. Scientia, 2005.
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KOČOVÁ M., NOVÁKOVÁ M. Vybrané úlohy ke cvičením z genetiky. Karolinum, Praha, 1997.
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SNUSTAD D.P., SIMMONS M.J. Genetika (český překlad). Masarykova univerzita Brno, 2017.
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