Technical University of Liberec
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for academic year 2023/2024
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Course: Selected chapters from genetics

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Course title Selected chapters from genetics
Course code KBE/VKG
Organizational form of instruction Lecture + Lesson
Level of course Master
Year of study not specified
Semester Winter
Number of ECTS credits 4
Language of instruction Czech, English
Status of course Compulsory, Compulsory-optional
Form of instruction Face-to-face
Work placements Course does not contain work placement
Recommended optional programme components None
Lecturer(s)
  • Hlaváčková Veronika, Mgr. Ph.D.
Course content
1. Introduction to genetics, history, fields of genetics 2. Basic concepts (gene, gene locus, genome, genotype, phenotype, allele, dominance, recessiveness, homozygote, heterozygote) 3. Mendel's laws 4. Gene interactions (intraallelic, interallelic, duplicate interactions, inheritance of quantitative traits, pleiotropy) 5. Gene linkage (Morgan's laws, crossing-over, linkage phases, linkage strength, gene mapping) 6. Genetic aspects of division (Cell cycle, mitosis and meiosis, sex-linked inheritance) 7. Cytological foundations of heredity (chromosome, karyotype, chromosomal sex determination) 8. Molecular foundations of heredity (structure of nucleic acids, chromatin, NK types, central dogma) 9. From information to phenotype (replication, transcription, translation, genetic code, differences between prokaryotic and eukaryotic systems) 10. Gene expression and its regulation at the level of transcription, post-transcription, translation and post-translation 11. Extranuclear inheritance, transmission of hereditary information 12. Fundamentals of population genetics - allogamous and autogamous populations, Hardy-Weinberg law, genetic drift 13. Mutation and mutagenesis - gene, chromosomal and genomic mutations, molecular nature of mutations, mutagens, repair of damaged DNA. 14. Methods of molecular genetics - DNA isolation, PCR, qPCR, genomics, proteomics, transcriptomics, sequencing, molecular cloning, model organisms in molecular biology

Learning activities and teaching methods
Self-study (text study, reading, problematic tasks, practical tasks, experiments, research, written assignments), Lecture, Practicum
  • Class attendance - 42 hours per semester
  • Preparation for credit - 30 hours per semester
  • Preparation for exam - 40 hours per semester
  • Class attendance - 12 hours per semester
  • Preparation for credit - 40 hours per semester
  • Preparation for exam - 60 hours per semester
Learning outcomes
The aim of the subject is to acquaint students with basic areas of genetics, principles of molecular genetic phenomena and basic molecular genetic methods.
Theoretical knowledge and practical skills in the field.
Prerequisites
basic knowledge of biology and chemistry

Assessment methods and criteria
Oral exam, Written assignment, Test

2x written test during the semester, the result will be included in the overall result of the exam, credit will be awarded for active participation in seminars and elaboration of laboratory protocols from individual tasks
Recommended literature
  • Kočárek E. Genetika. Scientia, 2005.
  • KOČOVÁ M., NOVÁKOVÁ M. Vybrané úlohy ke cvičením z genetiky. Karolinum, Praha, 1997.
  • SNUSTAD D.P., SIMMONS M.J. Genetika (český překlad). Masarykova univerzita Brno, 2017.
  • ZÁVODSKÁ R. Biologie buněk. Scientia, 2006.


Study plans that include the course
Faculty Study plan (Version) Category of Branch/Specialization Recommended year of study Recommended semester
Technical University of Liberec, date of update: 18.02.2025 23:50. Data created for academic year 2023/2024